Description
IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) is a synthetic recombinant analog of human IGF-1 structurally modified to enhance its stability and bioavailability in experimental models. By substituting an arginine at position 3 and extending the N-terminus amino acid chain, this analog significantly reduces its affinity for IGF-binding proteins (IGFBPs). This engineered delay results in a dramatically extended half-life and prolonged activity compared to native IGF-1.
In scientific and biochemical research, IGF-1 LR3 is widely utilized in in vitro assays to study cellular proliferation, cellular differentiation, and intracellular protein synthesis pathways, as well as its specific mechanisms within muscle cell cultures, neuronal growth, and tissue regeneration models.
Technical Specifications
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Peptide Name: IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1)
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Unit Size: 1mg per vial
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Physical Appearance: Crystalline lyophilized powder
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Molecular Weight: ~9111 Da
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Intended Use: For in vitro laboratory research and evaluation
Storage and Handling Protocols
To ensure the molecular integrity of the peptide and avoid premature degradation, strict adherence to the following storage conditions is highly recommended:
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Pre-Reconstitution (Dry Storage): Store in a dry, dark environment maintained between 2Β°C β 8Β°C. The lyophilized format is stable for short-term shipping at ambient temperature.
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Post-Reconstitution (Liquid Storage): Once reconstituted into solution, the material must be refrigerated consistently between 2Β°C β 8Β°C.
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Handling Note: Avoid aggressive agitation or shaking of the vial post-reconstitution to prevent structural shearing of the peptide chain.
Research Use Disclaimer This material is provided strictly for laboratory research use only. It is not intended, authorized, or approved for human clinical applications, diagnostic procedures, dietary supplementation, or veterinary use. All handling, reconstitution, and experimentation must be performed exclusively by qualified, trained professionals within an authorized research facility.






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