Description

N-Acetyl Semax Amidate is an advanced synthetic analog of Semax, a heptapeptide structurally derived from a fragment of the adrenocorticotropic hormone (ACTH). This specific analog has been chemically modified with an acetyl group at the N-terminus and an amide group at the C-terminus, structural variations engineered to significantly increase metabolic stability and resistance to enzymatic degradation within experimental assays.

In biochemical and neurological research settings, this compound is widely utilized to investigate melanocortin-receptor binding kinetics, neuroprotective mechanisms, and cellular signaling cascades—specifically focusing on its regulatory influence on Brain-Derived Neurotrophic Factor (BDNF) expression pathways.

Rise BioLabs supplies this specialized peptide in an ultra-pure, crystalline lyophilized state to preserve maximal chemical integrity and shelf-life during transit and storage.

Technical Specifications

Peptide Name: N-Acetyl Semax Amidate (Semax Analog)
Total Content: 10mg per vial
Physical Appearance: Lyophilized white powder
Purity Profile: $\ge 99\%$ (HPLC / MS certificate available upon request)
Target Applications: In vitro neurotrophic assays, BDNF-pathway tracking, and melanocortin-receptor modeling.

Storage and Handling Protocols

To safeguard the molecular integrity of the peptide chain and prevent premature degradation, adhere to the following laboratory storage protocols:

Pre-Reconstitution: Store in a cool, dry, and dark environment. The lyophilized powder remains fully stable at ambient temperatures during standard shipping.
Post-Reconstitution (Liquid State): Once mixed into solution, store consistently in a laboratory refrigerator between 2°C – 8°C and utilize within 30 days for optimal experimental results.
Extended Storage: For long-term preservation and maximum stability, aliquot the solution immediately after reconstitution and store frozen at -20°C or lower. Strictly avoid repeated freeze-thaw cycles to prevent structural degradation.

Research Use Disclaimer

This product is supplied exclusively to qualified professionals for in vitro laboratory research and development purposes only. It is not approved, authorized, or intended for human clinical applications, medical diagnostics, intranasal administration, or veterinary use. All handling must be conducted strictly within certified laboratory environments using appropriate personal protective equipment (PPE).